<?xml version="1.0" encoding="UTF-8"?><mets:mets xmlns:mads="http://www.loc.gov/mads/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:tef="http://www.abes.fr/abes/documents/tef" xmlns:metsRights="http://cosimo.stanford.edu/sdr/metsrights/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mets="http://www.loc.gov/METS/">
    <mets:metsHdr ID="rennes1-ori-wf-1-22258" CREATEDATE="2026-01-29T10:11:26" LASTMODDATE="2026-01-29T10:11:27">
  <mets:agent ROLE="CREATOR">
            <mets:name>Université de Rennes</mets:name>
        </mets:agent>
</mets:metsHdr>
    <mets:dmdSec ID="desc_expr" CREATED="2026-01-29T10:11:26">
  <mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_desc_these">
            <mets:xmlData>
                <tef:thesisRecord>
     <dc:title xml:lang="fr">La prise en charge de la thrombose veineuse au comptoir </dc:title>
     <dcterms:alternative xml:lang="en">The management of venous thrombosis at the counter </dcterms:alternative>
     <dc:subject xml:lang="fr">Thrombose veineuse profonde</dc:subject><dc:subject xml:lang="fr">anticoagulants</dc:subject><dc:subject xml:lang="fr">pharmacien d'officine</dc:subject><dc:subject xml:lang="fr">éducation thérapeutique du patient</dc:subject><dc:subject xml:lang="fr">observance</dc:subject><dc:subject xml:lang="fr">dispensation sécurisée</dc:subject><dc:subject xml:lang="fr">comptoir</dc:subject>
     <dc:subject xml:lang="en">Deep vein thrombosis</dc:subject><dc:subject xml:lang="en">anticoagulants</dc:subject><dc:subject xml:lang="en">dispensing pharmacist</dc:subject><dc:subject xml:lang="en">therapeutic patient education</dc:subject><dc:subject xml:lang="en">compliance</dc:subject><dc:subject xml:lang="en">secure dispensation</dc:subject><dc:subject xml:lang="en">counter</dc:subject>
     <tef:sujetRameau><tef:vedetteRameauNomCommun>
						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="174099061">Thrombose veineuse</tef:elementdEntree>
      <tef:subdivision autoriteSource="Sudoc" type="subdivisionDeSujet" autoriteExterne="027589838">Thérapeutique</tef:subdivision>
					</tef:vedetteRameauNomCommun><tef:vedetteRameauNomCommun>
						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="02765091X">Anticoagulants </tef:elementdEntree>
					</tef:vedetteRameauNomCommun><tef:vedetteRameauNomCommun>
						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="076696839">Dispensation (pharmacie)</tef:elementdEntree>
					</tef:vedetteRameauNomCommun><tef:vedetteRameauNomCommun>
						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027246639">Pharmaciens</tef:elementdEntree>
					</tef:vedetteRameauNomCommun><tef:vedetteRameauNomCommun>
						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="145909654">Conseil à l'officine</tef:elementdEntree>
					</tef:vedetteRameauNomCommun><tef:vedetteRameauNomCommun>
						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="027610586">Éducation des patients </tef:elementdEntree>
					</tef:vedetteRameauNomCommun><tef:vedetteRameauNomCommun>
						<tef:elementdEntree autoriteSource="Sudoc" autoriteExterne="031386318">Patients‎--Coopération </tef:elementdEntree>
					</tef:vedetteRameauNomCommun></tef:sujetRameau>
     
     
     
     
     
     
     <dcterms:abstract xml:lang="fr">La thrombose veineuse profonde, pathologie fréquente et potentiellement grave en raison du risque d’embolie pulmonaire, est majoritairement prise en charge en ambulatoire ce qui nécessite une vigilance accrue. Cette thèse rappelle les mécanismes, les facteurs de risque et l'arsenal thérapeutique (héparines, AVK, AOD), afin de donner au pharmacien les connaissances nécessaires pour prévenir, repérer et accompagner au mieux les patients à l’officine. L’intervention pharmaceutique est essentielle pour l'éducation thérapeutique et l'observance, afin de réduire le risque iatrogène. Cette approche met en lumière le rôle central du pharmacien dans la prévention, la sécurisation de la dispensation et la gestion des situations particulières afin d'améliorer le pronostic des patients en sécurisant la dispensation et le suivi au long cours. En assumant ces missions, le pharmacien devient un acteur pivot de la continuité et de la sécurité des soins en ville.</dcterms:abstract>
     <dcterms:abstract xml:lang="en">Deep vein thrombosis, a frequent and potentially serious condition due to the risk of pulmonary embolism, is mainly managed on an outpatient basis, which requires increased vigilance. This thesis recalls the mechanisms, risk factors and therapeutic arsenal (heparins, AVK, AOD), in order to give the pharmacist the necessary knowledge to prevent, identify and support patients at the pharmacy. Pharmaceutical intervention is essential for therapeutic education and adherence, in order to reduce iatrogenic risk. This approach highlights the central role of the pharmacist in prevention, securing dispensing and managing particular situations in order to improve patient prognosis by securing dispensation and long-term follow-up. By assuming these missions, the pharmacist becomes a pivotal actor in the continuity and safety of care in the city.</dcterms:abstract>
     <dc:type>Electronic Thesis or Dissertation</dc:type><dc:type xsi:type="dcterms:DCMIType">Text</dc:type>
     <dc:language xsi:type="dcterms:RFC3066">fr</dc:language>
    </tef:thesisRecord>
            </mets:xmlData>
        </mets:mdWrap>
</mets:dmdSec>
    <mets:dmdSec ID="desc_edition" CREATED="2026-01-29T10:11:26">
  <mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_desc_edition">
            <mets:xmlData>
                <tef:edition><dcterms:medium xsi:type="dcterms:IMT">application/pdf</dcterms:medium><dcterms:extent>1 : 3470 Ko</dcterms:extent><dc:identifier xsi:type="dcterms:URI">https://ged.univ-rennes1.fr/nuxeo/site/esupversions/bce7d43e-c48b-4128-b210-907db6c31946</dc:identifier></tef:edition>
            </mets:xmlData>
        </mets:mdWrap>
</mets:dmdSec>
    <mets:amdSec>
        <mets:techMD ID="admin_expr">
            <mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_admin_these">
                <mets:xmlData>
                    <tef:thesisAdmin>
                        <tef:auteur>
       <tef:nom>Muller</tef:nom>
       <tef:prenom>Maylis</tef:prenom>
       <tef:nomDeNaissance>Millet</tef:nomDeNaissance>
       <tef:dateNaissance>1997-07-30</tef:dateNaissance>
       <tef:nationalite scheme="ISO-3166-1">FR</tef:nationalite>
       <tef:autoriteExterne autoriteSource="Sudoc">298659077</tef:autoriteExterne>
       <tef:autoriteExterne autoriteSource="mailPerso">maylismillet@gmail.com</tef:autoriteExterne>
      </tef:auteur>
                        <dc:identifier xsi:type="tef:NNT">2026URENP003</dc:identifier>
                        <dc:identifier xsi:type="tef:nationalThesisPID">http://www.theses.fr/2026URENP003</dc:identifier>
                        <dcterms:dateAccepted xsi:type="dcterms:W3CDTF">2026-01-15</dcterms:dateAccepted>
                        <tef:thesis.degree>
                            <tef:thesis.degree.discipline xml:lang="fr">Pharmacie</tef:thesis.degree.discipline>
                            <tef:thesis.degree.grantor>
        <tef:nom>Universite de Rennes</tef:nom><tef:autoriteInterne>thesis.degree.grantor_1</tef:autoriteInterne>
        
        <tef:autoriteExterne autoriteSource="Sudoc">26693823X</tef:autoriteExterne>
       </tef:thesis.degree.grantor>
                            <tef:thesis.degree.level>Doctorat (thèse d'exercice)</tef:thesis.degree.level>
                        </tef:thesis.degree>
                        <tef:theseSurTravaux>non</tef:theseSurTravaux>
                        <tef:avisJury>oui</tef:avisJury><tef:directeurThese><tef:nom>Joannes </tef:nom><tef:prenom>Audrey </tef:prenom><tef:autoriteInterne>intervenant_1</tef:autoriteInterne><tef:autoriteExterne autoriteSource="Sudoc">180451081</tef:autoriteExterne></tef:directeurThese>
      
      
      
      
                        
                        <tef:oaiSetSpec>ddc:610</tef:oaiSetSpec>
                        
                    <tef:MADSAuthority authorityID="intervenant_1" type="personal"><tef:personMADS><mads:namePart type="family">Joannes </mads:namePart><mads:namePart type="given">Audrey </mads:namePart></tef:personMADS></tef:MADSAuthority><tef:MADSAuthority authorityID="thesis.degree.grantor_1" type="corporate"><tef:personMADS><mads:namePart>Universite de Rennes</mads:namePart><mads:description>Sciences et technologie, medecine, pharmacie, odontologie, droit, economie, gestion, philosophie</mads:description></tef:personMADS></tef:MADSAuthority></tef:thesisAdmin>
                </mets:xmlData>
            </mets:mdWrap>
        </mets:techMD><mets:techMD ID="file_1"><mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_tech_fichier"><mets:xmlData><tef:meta_fichier>
     <tef:encodage>ASCII</tef:encodage>
     <tef:formatFichier>PDF</tef:formatFichier>
     
     
     
     <tef:taille>3553318</tef:taille>
    </tef:meta_fichier></mets:xmlData></mets:mdWrap></mets:techMD>
        
        <mets:rightsMD ID="dr_expr_thesard">
            <mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_droits_auteur_these">
                <mets:xmlData>
                    <metsRights:RightsDeclarationMD>
                        <metsRights:RightsHolder>
                            <metsRights:RightsHolderName xsi:type="string">Maylis Muller </metsRights:RightsHolderName>
                        </metsRights:RightsHolder>
                        <metsRights:Context CONTEXTCLASS="GENERAL PUBLIC">
                            <metsRights:Permissions DISCOVER="true" DISPLAY="true" COPY="true" DUPLICATE="true" MODIFY="false" DELETE="false" PRINT="true"/>
                        </metsRights:Context>
                    </metsRights:RightsDeclarationMD>
                </mets:xmlData>
            </mets:mdWrap>
        </mets:rightsMD>
        <mets:rightsMD ID="dr_expr_univ">
            <mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_droits_etablissement_these">
                <mets:xmlData>
                    <metsRights:RightsDeclarationMD>
                        <metsRights:Context CONTEXTCLASS="GENERAL PUBLIC">
                            <metsRights:Permissions DISCOVER="true" DISPLAY="true" COPY="true" DUPLICATE="true" MODIFY="false" DELETE="false" PRINT="true"/>
                        </metsRights:Context>
                    </metsRights:RightsDeclarationMD>
                </mets:xmlData>
            </mets:mdWrap>
        </mets:rightsMD>
        <mets:rightsMD ID="dr_version">
            <mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_droits_version">
                <mets:xmlData>
                    <metsRights:RightsDeclarationMD>
                        <metsRights:Context CONTEXTCLASS="GENERAL PUBLIC">
                            <metsRights:Permissions DISCOVER="true" DISPLAY="true" COPY="true" DUPLICATE="true" MODIFY="false" DELETE="false" PRINT="true"/>
                        </metsRights:Context>
                    </metsRights:RightsDeclarationMD>
                </mets:xmlData>
            </mets:mdWrap>
        </mets:rightsMD>
    </mets:amdSec>
    <mets:fileSec>
  <mets:fileGrp ID="FGrID1" USE="archive"><mets:file ID="FID1" ADMID="file_1" MIMETYPE="application/pdf" USE="maitre"><mets:FLocat LOCTYPE="URL" xlink:href="https://ged.univ-rennes1.fr/nuxeo/site/esupversions/bce7d43e-c48b-4128-b210-907db6c31946"/></mets:file></mets:fileGrp>
 </mets:fileSec>
    <mets:structMap TYPE="logical">
        <mets:div DMDID="desc_expr" ADMID="dr_expr_thesard dr_expr_univ admin_expr" TYPE="THESE" CONTENTIDS="http://ori-oai-search.univ-rennes1.fr/uid/rennes1-ori-wf-1-22258/oeuvre">
            <mets:div ADMID="dr_version" TYPE="VERSION_COMPLETE" CONTENTIDS="http://ori-oai-search.univ-rennes1.fr/uid/rennes1-ori-wf-1-22258/oeuvre/version">
                <mets:div DMDID="desc_edition" TYPE="EDITION" CONTENTIDS="http://ori-oai-search.univ-rennes1.fr/uid/rennes1-ori-wf-1-22258/oeuvre/version/edition">
                    <mets:fptr FILEID="FGrID1"/>
                </mets:div>
            </mets:div>
        </mets:div>
    </mets:structMap>
</mets:mets>