<?xml version="1.0" encoding="UTF-8"?><metadata>
<lom xmlns="http://ltsc.ieee.org/xsd/LOM" xmlns:lomfr="http://www.lom-fr.fr/xsd/LOMFR" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://ltsc.ieee.org/xsd/LOM http://www.lom-fr.fr/xsd/lomfrv1.0/std/lomfr.xsd">
<general>
    <identifier>
        <catalog>Canal-U_Ocms</catalog>
        <entry>11511</entry>
    </identifier>
    <title><string language="fre"><![CDATA[Age of acquisition affects word retrieval in spontaneous speech produced by patients with Alzheimer's disease / Frédérique Gayraud, Mélissa Barkat-Defradas]]></string></title>
    <language>FRE</language>
    <description>
        <string language="fre"><![CDATA[Age of acquisition affects word retrieval in spontaneous speech produced by patients with Alzheimer's disease / Frédérique Gayraud, Mélissa Barkat-Defradas. In "Perspectives neuropsycholinguistiques sur l'aphasie - NeuroPsychoLinguistic Perspectives on Aphasia", colloque international organisé par l'Unité de Recherche Interdisciplinaire Octogone de l'Université Toulouse II-Le Mirail (France). Toulouse, 21-23 juin 2012. 
Typical assessment of language in Alzheimer’s disease typically relies on experimental tasks such as confrontation naming or fluency tasks. These widely used methods show several advantages such as rapidity of assessment, standardization and good control for a set of important psycholinguistic variables. However some studies suggest that analysis of discourse may be better than naming tasks for assessing everyday word-finding difficulties in elderly adults (Schmitter-Edgecombe et al. (2000). 
Several psycholinguistic variables are known to affect word retrieval on both normal and pathological populations among which Age of Acquisition (henceforth AoA): words acquired earlier are easier and faster to process than words acquired later (Bates et al., 2001; Hodgson & Ellis, 1998; Lymperopoulo et al., 2006). This variable has so far received little attention in the Alzheimer’s population although it has been proposed as a possible early marker of the disease (Forbes-McKay, et al., 2005). 
Twenty participants diagnosed with Alzheimer’s disease and twenty healthy controls matched for age, sex, level of education and socioeconomic status participated in our study.  Spontaneous speech data were elicited by asking participants about biographical details. Any silence exceeding 200 ms was coded as a silent pause. Filled pauses, vocalic lengthenings and hesitations were also measured. These different dysfluencies were used to identify words prone to retrieval difficulty. 
For each text, a number of problematic words were identified, and a set of the same number of unproblematic words was randomly selected. 49 native French-speaking adults rated AoA on a 7-grade scale for the two word lists. In addition the frequency of each word was computed using the Lexique Database (New et al., 2004). 
Results reveal that problematic and non-problematic words do not significantly differ in frequency. Similarly no effect of frequency is observed between the two groups of participants. Turning to AoA, we find a group effect: problematic words produced by patients are acquired significantly later than the ones produced by healthy subjects. Similarly, in the Alzheimer’s group, problematic words are acquired significantly later than non-problematic words while the difference is not significant in the control group. We discuss our results in the framework of the retrogenesis hypothesis (Reisberg, Franssen, Auer, Akram & Kenowsky, 2002).]]></string></description>
    <keyword><string language="fre"><![CDATA[maladie d'Alzheimer]]></string></keyword><keyword><string language="fre"><![CDATA[troubles du langage]]></string></keyword><keyword><string language="fre"><![CDATA[aphasie]]></string></keyword>
    <lomfr:documentType>
        <lomfr:source>LOMFRv1.0</lomfr:source>
        <lomfr:value>image en mouvement</lomfr:value>
    </lomfr:documentType>
</general><lifeCycle>
    
    <contribute>
            <role>
                <source>LOMv1.0</source>
                <value>content provider</value>
            </role>
            <entity><![CDATA[BEGIN:VCARD
VERSION:3.0
CLASS:PUBLIC
REV:2015-01-04 00:00:24
FN:Bruno BASTARD
N:BASTARD;Bruno;;;

URL;TYPE=work:http://www.canal-u.tv/auteurs/bastard_bruno
ROLE:content provider
NOTE:                                Statut           Réalisateur                        
TZ:+0100
END:VCARD
]]></entity>
            <date><dateTime>2012-06-22</dateTime></date>
        </contribute>

    <contribute>
            <role>
                <source>LOMv1.0</source>
                <value>publisher</value>
            </role>
            <entity><![CDATA[BEGIN:VCARD
VERSION:3.0
CLASS:PUBLIC
REV:2015-01-04 00:00:24
FN:Université Toulouse II-Le Mirail
N:Université Toulouse II-Le Mirail;;;;

URL;TYPE=work:http://www.univ-tlse2.fr/
ROLE:publisher
TZ:+0100
END:VCARD
]]></entity>
            <date><dateTime>2012-06-22</dateTime></date>
        </contribute>

    <contribute>
            <role>
                <source>LOMv1.0</source>
                <value>content provider</value>
            </role>
            <entity><![CDATA[BEGIN:VCARD
VERSION:3.0
CLASS:PUBLIC
REV:2015-01-04 00:00:24
FN:Université Toulouse II-Le Mirail SCPAM
N:SCPAM;Université Toulouse II-Le Mirail;;;

URL;TYPE=work:http://www.canal-u.tv/auteurs/scpam_universite_toulouse_ii_le_mirail
ROLE:content provider
NOTE:  Service de Conception et de Production Audiovisuelle et Multimédia de l'Université Toulouse II-Le Mirail, rattaché à la Direction des Technologies de l'Information et de la Communication pour l'Enseignement.
TZ:+0100
END:VCARD
]]></entity>
            <date><dateTime>2012-06-22</dateTime></date>
        </contribute>

    <contribute>
            <role>
                <source>LOMv1.0</source>
                <value>author</value>
            </role>
            <entity><![CDATA[BEGIN:VCARD
VERSION:3.0
CLASS:PUBLIC
REV:2015-01-04 00:00:24
FN:Frédérique GAYRAUD
N:GAYRAUD;Frédérique;;;

URL;TYPE=work:http://www.canal-u.tv/auteurs/gayraud_frederique
ROLE:author
NOTE:Frédérique Gayraud est Maître de conférences et membre du laboratoire Dynamique du langage à l'Université Lyon 2 (France). Ses recherches portent notamment sur le traitement cognitif de la complexité syntaxique,&nbsp;Langage et maladie d'Alzheimer, l'acquisition du lexique précoce, etc.&gt; Voir sa page personnelle (DDL, Lyon 2).
TZ:+0100
END:VCARD
]]></entity>
            <date><dateTime>2012-06-22</dateTime></date>
        </contribute>

    <contribute>
            <role>
                <source>LOMv1.0</source>
                <value>author</value>
            </role>
            <entity><![CDATA[BEGIN:VCARD
VERSION:3.0
CLASS:PUBLIC
REV:2015-01-04 00:00:24
FN:Melissa BARKAT-DEFRADAS
N:BARKAT-DEFRADAS;Melissa;;;

URL;TYPE=work:http://www.canal-u.tv/auteurs/barkat_defradas_melissa
ROLE:author
NOTE:Melissa Barkat-Defradas est chargée de recherche au sein de l'équipe de recherche&nbsp;Praxiling&nbsp;à l'Université Paul-Valéry-Montpellier 3 (France) où elle est responsable scientifique de l'axe d'étude "Discours, Langues &amp; Interculturalité" et spécialiste du&nbsp;domaine linguistique et culturel arabe.&gt; Voir sa page personnelle (DDL, Lyon 2).
TZ:+0100
END:VCARD
]]></entity>
            <date><dateTime>2012-06-22</dateTime></date>
        </contribute>

</lifeCycle>
<metaMetadata>
    <metadataSchema>LOMv1.0</metadataSchema>
    <metadataSchema>LOMFRv1.0</metadataSchema>
</metaMetadata>
<technical>
    <format>video/x-flv</format>
    <location><![CDATA[http://www.canal-u.tv/video/universite_toulouse_ii_le_mirail/age_of_acquisition_affects_word_retrieval_in_spontaneous_speech_produced_by_patients_with_alzheimer_s_disease_frederique_gayraud_melissa_barkat_defradas.11511]]></location>
    <location><![CDATA[rtmpt://fms2.cerimes.fr:80/vod/utm/age.of.acquisition.affects.word.retrieval.in.spontaneous.speech.produced.by.patients.with.alzheimer.s.disease.fr.d.rique.gayraud.m.lissa.barkat.defradas_11511/6.aphasia.f.gayraud.et.m.barka.defradas.mp4]]></location>
        
        
    <size>200893458</size>
    <duration><duration>PT0H23M41S</duration></duration>
</technical>
<educational>
    <learningResourceType>
        <source>LOMv1.0</source>
        <value>lecture</value>
    </learningResourceType>
    
</educational>
<rights>
    <cost>
        <source>LOMv1.0</source>
        <value>no</value>
    </cost>
    <copyrightAndOtherRestrictions>
        <source>LOMv1.0</source>
        <value>no</value>
    </copyrightAndOtherRestrictions>
    <description>
        <string language="fre"><![CDATA[Droits réservés à l&#039;éditeur et aux auteursTous droits réservés à l'Université Toulouse II-Le Mirail et aux auteurs.]]></string>
    </description>
</rights>

            <relation>
                <kind>
                    <source>LOMv1.0</source>
                    <value>ispartof</value>
                </kind>
                <resource>
                    <identifier>
                        <catalog>URI</catalog>
                        <entry>http://www.canal-u.tv/producteurs/universite_toulouse_ii_le_mirail/colloques/perspectives_neuropsycholinguistiques_sur_l_aphasie</entry>
                    </identifier>
                    <description>
                        <string language="fre">Perspectives neuropsycholinguistiques sur l'aphasie</string>
                    </description>
                </resource>
            </relation>

<classification>
    <purpose>
        <source>LOMv1.0</source>
        <value>discipline</value>
    </purpose>
    <taxonPath>
        <source>
        <string language="fre">Universités Numériques Thématiques 2009 http://www.universites-numeriques.fr</string>
        </source>
        <taxon>
            <id/>
            <entry>
                <string language="fre"/>
            </entry>
        </taxon>
    </taxonPath>
</classification>
<classification>
    <purpose>
        <source>LOMv1.0</source>
        <value>discipline</value>
    </purpose>
    
    <taxonPath>
        <source>
            <string language="fre">CDD 22e éd.</string>
            <string language="eng">DDC 22nd ed.</string>
        </source>
        <taxon>
            <id>401.9</id>
            <entry>
                <string language="fre">Psycholinguistique</string>
            </entry>
        </taxon>
   </taxonPath>
    <taxonPath>
        <source>
            <string language="fre">CDD 22e éd.</string>
            <string language="eng">DDC 22nd ed.</string>
        </source>
        <taxon>
            <id>616.855</id>
            <entry>
                <string language="fre">Troubles de la parole et du langage (troubles de la communication, de l'articulation ; orthophonie)</string>
            </entry>
        </taxon>
   </taxonPath>
</classification>      </lom>
   </metadata>